Sunday, June 20, 2010

SLEEPING BEAUTY SYNDROME

Posted by LIMBERELLA at 6/20/2010 10:37:00 PM


I always love to sleep (who doesn't). I always find time for sleep. Even a few minutes nap would do. This is my way of indulging my exasperation, my way of rest and sometimes my form of escape. But to sleep forever...NO WAY!

Sleeping is good and relaxing, although sometimes it can cause you instant headache when you're "overdose" with it. But what if one ordinary day, you woke up and realize that you've already been sleeping for 18 hours?... Now that's alarming!

I have read over the internet that there is what we call Kleine-Levin Syndrome or KLS (also known as Sleeping Beauty Syndrome). For more information, I would like to share to you a little research I made.

It is a neurological disorder characterized by recurring periods of excessive amounts of sleep and altered behavior. At the onset of an episode the patient becomes drowsy and sleeps for most of the day and night (hypersomnolence), waking only to eat or go to the bathroom. When awake, the patient’s whole demeanor is changed, often appearing “spacey” or childlike. They also experience confusion, disorientation, complete lack of energy (lethargy), and lack of emotions (apathy). Individuals are not able to attend school or work or care for themselves. Most are bedridden, tired, and uncommunicative even when awake.
Most patients report that everything seems out of focus, and that they are hypersensitive to noise and light. In some cases, food cravings (compulsive hyperphagia) are exhibited. Instances of uninhibited hypersexuality during episodes (mostly males) and instances of depression (mostly females) have also been reported. Most cases of Kleine-Levin syndrome are seen in teenage boys.[1]

Affected individuals may go for a period of weeks, months or even years without experiencing any symptoms, and then they reappear with little warning. In between episodes those diagnosed with KLS appear to be in perfect health with no evidence of behavioral or physical dysfunction.
The cause of Kleine-Levin syndrome is not known. Thus, family support and education are the best management currently available.

CAUSES
While some researchers speculate that there may be a hereditary predisposition, others believe the condition may be the result of an autoimmune disorder.[6] Both proposals need not be mutually exclusive with the result being a malfunction of the portion of the brain that helps to regulate functions such as sleep, appetite, and body temperature (hypothalamus).[7] Recent studies also suggest that there may be a link to a deficiency of dopamine transporter density in the lower striatum.

SYMPTOMS
Hypersomnia is a primary symptom of KLS, and is present in all subjects. Subjects are often treated initially for a sleeping disorder. During a KLS episode, subjects often spend 18 hours a day asleep. Another defining symptom of KLS is an altered mental state during the episode. Subjects are hard to arouse from this sleep, and are irritable or aggressive when prevented from sleeping. Subjects also frequently show cognitive impairment[12], and can show confusion, amnesia for the event, hallucinations, delusions, or experience a dream-like state. About 75% of KLS patients experience changes in eating behavior during episodes, with the majority of these exhibiting megaphagia. Reports describe patients who will eat anything placed in front of them with very little discrimination, including consumption of excessive amounts of food. Almost half of KLS patients also experience some sort of hypersexual behavior during the event, including promiscuity, excessive masturbation, inappropriate sexual advances, and other risqué, atypical behavior. Hypersexual behavior is more common in males than females, and is associated with a much longer disease course.[13] Other unusual compulsions reported during the event are also not uncommon.


SO, DO YOU STILL WANT TO SLEEP?..=)

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